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Relative Contribution of Dengue IgG Antibodies Acquired during Gestation or Breastfeeding in Mediating Dengue Disease Enhancement and Protection in Type I Interferon Receptor-Deficient Mice

Dengue virus (DENV) causes a spectrum of diseases ranging from self-limiting dengue fever to severe conditions such as haemorrhagic fever and dengue shock syndrome. Antibody-dependent enhancement (ADE) is thought to explain the occurrence of severe dengue whereby pre-existing binding but non-neutral...

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Detalles Bibliográficos
Autores principales: Lee, Pei Xuan, Ong, Li Ching, Libau, Eshele Anak, Alonso, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920417/
https://www.ncbi.nlm.nih.gov/pubmed/27341339
http://dx.doi.org/10.1371/journal.pntd.0004805