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Expression of the retinoic acid catabolic enzyme CYP26B1 in the human brain to maintain signaling homeostasis

Retinoic acid (RA) is a potent regulator of gene transcription via its activation of a set of nuclear receptors controlling transcriptional activation. Precise maintenance of where and when RA is generated is essential and achieved by local expression of synthetic and catabolic enzymes. The cataboli...

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Detalles Bibliográficos
Autores principales: Stoney, Patrick N., Fragoso, Yara D., Saeed, Reem Bu, Ashton, Anna, Goodman, Timothy, Simons, Claire, Gomaa, Mohamed S., Sementilli, Angelo, Sementilli, Leonardo, Ross, Alexander W., Morgan, Peter J., McCaffery, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920859/
https://www.ncbi.nlm.nih.gov/pubmed/26374207
http://dx.doi.org/10.1007/s00429-015-1102-z