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Pharmaceutical inhibition of mTOR in the common marmoset: effect of rapamycin on regulators of proteostasis in a non-human primate

BACKGROUND: Inhibition of mechanistic target of rapamycin (mTOR) has emerged as a viable means to lengthen lifespan and healthspan in mice, although it is still unclear whether these benefits will extend to other mammalian species. We previously reported results from a pilot experiment wherein commo...

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Detalles Bibliográficos
Autores principales: Lelegren, Matthew, Liu, Yuhong, Ross, Corinna, Tardif, Suzette, Salmon, Adam B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920937/
https://www.ncbi.nlm.nih.gov/pubmed/27341957
http://dx.doi.org/10.3402/pba.v6.31793