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Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line

BACKGROUND: Crocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. Multidrug resistance-associated proteins 1 and 2 (MRP1 and MRP2) are important elements in the failure of cancer chemotherapy. In this study we aimed to evaluate the effe...

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Detalles Bibliográficos
Autores principales: Mahdizadeh, Shadi, Karimi, Gholamreza, Behravan, Javad, Arabzadeh, Sepideh, Lage, Hermann, Kalalinia, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920992/
https://www.ncbi.nlm.nih.gov/pubmed/27342070
http://dx.doi.org/10.1186/s40199-016-0155-8