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Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders

Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease. It has since emerged as a major risk factor (causative gene) for Alzheimer’s disease and other ne...

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Detalles Bibliográficos
Autor principal: Mahley, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921111/
https://www.ncbi.nlm.nih.gov/pubmed/27277824
http://dx.doi.org/10.1007/s00109-016-1427-y