Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective

Gemcitabine is an antimetabolite ranking among the most prescribed anticancer drugs worldwide. This nucleoside analog exerts its antiproliferative action after tumoral conversion into active triphosphorylated nucleotides interfering with DNA synthesis and targeting ribonucleotide reductase. Gemcitab...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciccolini, Joseph, Serdjebi, Cindy, Peters, Godefridus J., Giovannetti, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921117/
https://www.ncbi.nlm.nih.gov/pubmed/27007129
http://dx.doi.org/10.1007/s00280-016-3003-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921117/
https://www.ncbi.nlm.nih.gov/pubmed/27007129
http://dx.doi.org/10.1007/s00280-016-3003-0

Ejemplares similares