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One Month of Oral Morphine Decreases Gray Matter Volume in the Right Amygdala of Individuals with Low Back Pain: Confirmation of Previously Reported Magnetic Resonance Imaging Results

Objective. Prolonged exposure to opioids is known to produce neuroplastic changes in animals; however, few studies have investigated the effects of short-term prescription opioid use in humans. A previous study from our laboratory demonstrated a dosage-correlated volumetric decrease in the right amy...

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Detalles Bibliográficos
Autores principales: Lin, Joanne C., Chu, Larry F., Stringer, Elizabeth Ann, Baker, Katharine S., Sayyid, Zahra N., Sun, John, Campbell, Kelsey A., Younger, Jarred W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921346/
https://www.ncbi.nlm.nih.gov/pubmed/26814280
http://dx.doi.org/10.1093/pm/pnv047