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PGC-1α expression in murine AgRP neurons regulates food intake and energy balance

OBJECTIVE: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP) and pro-opiomelanocortin (POMC) neurons located in the arcuate nucleus of the hypothalamus. Key energy sensors, such as the AMP-activated protein kinase (AMPK) or sirtuin 1 (SIRT1), are essential...

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Detalles Bibliográficos
Autores principales: Gill, Jonathan F., Delezie, Julien, Santos, Gesa, Handschin, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921790/
https://www.ncbi.nlm.nih.gov/pubmed/27408781
http://dx.doi.org/10.1016/j.molmet.2016.05.008