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AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue

OBJECTIVE: Characterize the cellular and molecular events responsible for lipodystrophy in AGPAT2 deficient mice. METHODS: Adipose tissue and differentiated MEF were assessed using light and electron microscopy, followed by protein (immunoblots) and mRNA analysis (qPCR). Phospholipid profiling was d...

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Detalles Bibliográficos
Autores principales: Cautivo, Kelly M., Lizama, Carlos O., Tapia, Pablo J., Agarwal, Anil K., Garg, Abhimanyu, Horton, Jay D., Cortés, Víctor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921804/
https://www.ncbi.nlm.nih.gov/pubmed/27408775
http://dx.doi.org/10.1016/j.molmet.2016.05.004