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Calcitonin attenuates cartilage degeneration and nociception in an experimental rat model of osteoarthritis: role of TGF-β in chondrocytes

We investigated the role of the calcitonin (Miacalcin) in the progression of osteoarthritis (OA) and in nociceptive behavior in an experimental rat model of OA and osteoporosis. OA was induced by anterior cruciate ligament transection (ACLT) of the right knee and by bilateral ovariectomy (OVX) in Wi...

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Detalles Bibliográficos
Autores principales: Wen, Zhi-Hong, Tang, Chi-Chieh, Chang, Yi-Chen, Huang, Shi-Ying, Lin, Yen-You, Hsieh, Shih-Peng, Lee, Hsin-Pai, Lin, Sung-Chun, Chen, Wu-Fu, Jean, Yen-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921823/
https://www.ncbi.nlm.nih.gov/pubmed/27345362
http://dx.doi.org/10.1038/srep28862