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Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA

Under hypertrophic stimulation, cardiomyocytes enter a hypermetabolic state and accelerate biomass accumulation. Although the molecular pathways that regulate protein levels are well-studied, the functional implications of RNA accumulation and its regulatory mechanisms in cardiomyocytes remain elusi...

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Detalles Bibliográficos
Autores principales: Masumura, Yuki, Higo, Shuichiro, Asano, Yoshihiro, Kato, Hisakazu, Yan, Yi, Ishino, Saki, Tsukamoto, Osamu, Kioka, Hidetaka, Hayashi, Takaharu, Shintani, Yasunori, Yamazaki, Satoru, Minamino, Tetsuo, Kitakaze, Masafumi, Komuro, Issei, Takashima, Seiji, Sakata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921833/
https://www.ncbi.nlm.nih.gov/pubmed/27346836
http://dx.doi.org/10.1038/srep28592