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Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA
Under hypertrophic stimulation, cardiomyocytes enter a hypermetabolic state and accelerate biomass accumulation. Although the molecular pathways that regulate protein levels are well-studied, the functional implications of RNA accumulation and its regulatory mechanisms in cardiomyocytes remain elusi...
Autores principales: | Masumura, Yuki, Higo, Shuichiro, Asano, Yoshihiro, Kato, Hisakazu, Yan, Yi, Ishino, Saki, Tsukamoto, Osamu, Kioka, Hidetaka, Hayashi, Takaharu, Shintani, Yasunori, Yamazaki, Satoru, Minamino, Tetsuo, Kitakaze, Masafumi, Komuro, Issei, Takashima, Seiji, Sakata, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921833/ https://www.ncbi.nlm.nih.gov/pubmed/27346836 http://dx.doi.org/10.1038/srep28592 |
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