3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway

The epithelial to mesenchymal transition (EMT) is a critical developmental program in cancer stem cell (CSC) maintenance and in cancer metastasis. Here, our study found that 3,6-DHF could effectively inhibit EMT in BC cells in vitro and in vivo. 3,6-DHF effectively inhibits the formation and prolife...

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Detalles Bibliográficos
Autores principales: Chen, Junli, Chang, Hui, Peng, Xiaoli, Gu, Yeyun, Yi, Long, Zhang, Qianyong, Zhu, Jundong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921838/
https://www.ncbi.nlm.nih.gov/pubmed/27345219
http://dx.doi.org/10.1038/srep28858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921838/
https://www.ncbi.nlm.nih.gov/pubmed/27345219
http://dx.doi.org/10.1038/srep28858

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