CTCF contributes in a critical way to spermatogenesis and male fertility

The CCCTC-binding factor (CTCF) is an architectural protein that governs chromatin organization and gene expression in somatic cells. Here, we show that CTCF regulates chromatin compaction necessary for packaging of the paternal genome into mature sperm. Inactivation of Ctcf in male germ cells in mi...

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Detalles Bibliográficos
Autores principales: Hernández-Hernández, Abrahan, Lilienthal, Ingrid, Fukuda, Nanaho, Galjart, Niels, Höög, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921845/
https://www.ncbi.nlm.nih.gov/pubmed/27345455
http://dx.doi.org/10.1038/srep28355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921845/
https://www.ncbi.nlm.nih.gov/pubmed/27345455
http://dx.doi.org/10.1038/srep28355

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