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Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin

α-hemolysin (Hla) is a self-assembling extracellular protein secreted as a soluble monomer by most Staphylococcus aureus strains and is an essential virulence factor for the pathogenesis of various S. aureus infections. Here, we show that curcumin (CUR), a natural compound with weak anti-S. aureus a...

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Detalles Bibliográficos
Autores principales: Wang, Jianfeng, Zhou, Xuan, Li, Wenhua, Deng, Xuming, Deng, Yanhong, Niu, Xiaodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921848/
https://www.ncbi.nlm.nih.gov/pubmed/27345357
http://dx.doi.org/10.1038/srep28254