Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders

The secreted glycoprotein Reelin is believed to play critical roles in the pathogenesis of several neuropsychiatric disorders. The highly basic C-terminal region (CTR) of Reelin is necessary for efficient activation of its downstream signaling, and the brain structure of knock-in mice that lack the...

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Detalles Bibliográficos
Autores principales: Sakai, Kaori, Shoji, Hirotaka, Kohno, Takao, Miyakawa, Tsuyoshi, Hattori, Mitsuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921851/
https://www.ncbi.nlm.nih.gov/pubmed/27346785
http://dx.doi.org/10.1038/srep28636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921851/
https://www.ncbi.nlm.nih.gov/pubmed/27346785
http://dx.doi.org/10.1038/srep28636

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