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Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders
The secreted glycoprotein Reelin is believed to play critical roles in the pathogenesis of several neuropsychiatric disorders. The highly basic C-terminal region (CTR) of Reelin is necessary for efficient activation of its downstream signaling, and the brain structure of knock-in mice that lack the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921851/ https://www.ncbi.nlm.nih.gov/pubmed/27346785 http://dx.doi.org/10.1038/srep28636 |