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Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice

Generation of orthotopic xenograft mouse models of leukemia is important to understand the mechanisms of leukemogenesis, cancer progression, its cross talk with the bone marrow microenvironment, and for preclinical evaluation of drugs. In these models, following intravenous injection, leukemic cells...

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Detalles Bibliográficos
Autores principales: Gopalakrishnapillai, Anilkumar, Kolb, E. Anders, Dhanan, Priyanka, Bojja, Aruna Sri, Mason, Robert W., Corao, Diana, Barwe, Sonali P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921874/
https://www.ncbi.nlm.nih.gov/pubmed/27446808
http://dx.doi.org/10.3389/fonc.2016.00162