Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABA(A) receptors: evidence of a novel benzodiazepine site in the α1-α1 interface

Zolpidem is not a typical GABA(A) receptor hypnotic. Unlike benzodiazepines, zolpidem modulates tonic GABA currents in the rat dorsal motor nucleus of the vagus, exhibits residual effects in mice lacking the benzodiazepine binding site, and improves speech, cognitive and motor function in human pati...

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Detalles Bibliográficos
Autores principales: Che Has, Ahmad Tarmizi, Absalom, Nathan, van Nieuwenhuijzen, Petra S., Clarkson, Andrew N., Ahring, Philip K., Chebib, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921915/
https://www.ncbi.nlm.nih.gov/pubmed/27346730
http://dx.doi.org/10.1038/srep28674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921915/
https://www.ncbi.nlm.nih.gov/pubmed/27346730
http://dx.doi.org/10.1038/srep28674

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