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A Role for Nuclear Actin in HDAC 1 and 2 Regulation

Class I histone deacetylases (HDACs) are known to remove acetyl groups from histone tails. This liberates positive charges on the histone tail and allows for tighter winding of DNA, preventing transcription factor binding and gene activation. Although the functions of HDAC proteins are becoming appa...

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Detalles Bibliográficos
Autores principales: Serebryannyy, Leonid A., Cruz, Christina M., de Lanerolle, Primal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921920/
https://www.ncbi.nlm.nih.gov/pubmed/27345839
http://dx.doi.org/10.1038/srep28460