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A Role for Nuclear Actin in HDAC 1 and 2 Regulation
Class I histone deacetylases (HDACs) are known to remove acetyl groups from histone tails. This liberates positive charges on the histone tail and allows for tighter winding of DNA, preventing transcription factor binding and gene activation. Although the functions of HDAC proteins are becoming appa...
Autores principales: | Serebryannyy, Leonid A., Cruz, Christina M., de Lanerolle, Primal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921920/ https://www.ncbi.nlm.nih.gov/pubmed/27345839 http://dx.doi.org/10.1038/srep28460 |
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