DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma

Studies indicate that the presence of cancer stem cells (CSCs) is responsible for poor prognosis of hepatocellular carcinoma (HCC) patients. In this study, the functional role of DDX3 in regulation of hepatic CSCs was investigated. Our results demonstrated that reduced DDX3 expression was not only i...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hao-Kang, Mai, Ru-Tsun, Huang, Hsien-Da, Chou, Chih-Hung, Chang, Yi-An, Chang, Yao-Wen, You, Li-Ru, Chen, Chun-Ming, Lee, Yan-Hwa Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921922/
https://www.ncbi.nlm.nih.gov/pubmed/27344963
http://dx.doi.org/10.1038/srep28637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921922/
https://www.ncbi.nlm.nih.gov/pubmed/27344963
http://dx.doi.org/10.1038/srep28637

Ejemplares similares