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Thiazine Red(+) platelet inclusions in Cerebral Blood Vessels are first signs in an Alzheimer’s Disease mouse model

Strong evidence shows an association between cerebral vascular diseases and Alzheimer´s disease (AD). In order to study the interaction of beta-amyloid (Aβ) plaques with brain vessels, we crossbred an AD mouse model (overexpressing amyloid precursor protein with the Swedish-Dutch-Iowa mutations, APP...

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Detalles Bibliográficos
Autores principales: Kniewallner, Kathrin M., Wenzel, Daniela, Humpel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921929/
https://www.ncbi.nlm.nih.gov/pubmed/27345467
http://dx.doi.org/10.1038/srep28447