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A previously unrecognized role of C3a in proteinuric progressive nephropathy

Podocyte loss is the initial event in the development of glomerulosclerosis, the structural hallmark of progressive proteinuric nephropathies. Understanding mechanisms underlying glomerular injury is the key challenge for identifying novel therapeutic targets. In mice with protein-overload induced b...

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Detalles Bibliográficos
Autores principales: Morigi, Marina, Locatelli, Monica, Rota, Cinzia, Buelli, Simona, Corna, Daniela, Rizzo, Paola, Abbate, Mauro, Conti, Debora, Perico, Luca, Longaretti, Lorena, Benigni, Ariela, Zoja, Carlamaria, Remuzzi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921969/
https://www.ncbi.nlm.nih.gov/pubmed/27345360
http://dx.doi.org/10.1038/srep28445