N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel

Human transient receptor potential ankyrin channel 1 (TRPA1) is a polymodal sensor implicated in pain, inflammation and itching. An important locus for TRPA1 regulation is the cytoplasmic N-terminal domain, through which various exogenous electrophilic compounds such as allyl-isothiocyanate from mus...

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Detalles Bibliográficos
Autores principales: Hynkova, Anna, Marsakova, Lenka, Vaskova, Jana, Vlachova, Viktorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922051/
https://www.ncbi.nlm.nih.gov/pubmed/27345869
http://dx.doi.org/10.1038/srep28700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922051/
https://www.ncbi.nlm.nih.gov/pubmed/27345869
http://dx.doi.org/10.1038/srep28700

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