Mitochondrial heteroplasmy in vertebrates using ChIP-sequencing data

BACKGROUND: Mitochondrial heteroplasmy, the presence of more than one mitochondrial DNA (mtDNA) variant in a cell or individual, is not as uncommon as previously thought. It is mostly due to the high mutation rate of the mtDNA and limited repair mechanisms present in the mitochondrion. Motivated by...

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Detalles Bibliográficos
Autores principales: Rensch, Thomas, Villar, Diego, Horvath, Julie, Odom, Duncan T., Flicek, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922064/
https://www.ncbi.nlm.nih.gov/pubmed/27349964
http://dx.doi.org/10.1186/s13059-016-0996-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922064/
https://www.ncbi.nlm.nih.gov/pubmed/27349964
http://dx.doi.org/10.1186/s13059-016-0996-y

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