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Mitochondrial heteroplasmy in vertebrates using ChIP-sequencing data
BACKGROUND: Mitochondrial heteroplasmy, the presence of more than one mitochondrial DNA (mtDNA) variant in a cell or individual, is not as uncommon as previously thought. It is mostly due to the high mutation rate of the mtDNA and limited repair mechanisms present in the mitochondrion. Motivated by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922064/ https://www.ncbi.nlm.nih.gov/pubmed/27349964 http://dx.doi.org/10.1186/s13059-016-0996-y |