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IL-17A and TNF-α Increase the Expression of the Antiapoptotic Adhesion Molecule Amigo-2 in Arthritis Synoviocytes

Rheumatoid arthritis (RA) is a chronic inflammatory disorder, characterized by a persistent immune cell infiltrate in the synovium accompanied by high levels of inflammatory mediators and synovial hyperplasia. Despite significant therapeutic advances, RA remains an important unmet medical need. To d...

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Detalles Bibliográficos
Autores principales: Benedetti, Giulia, Bonaventura, Paola, Lavocat, Fabien, Miossec, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922130/
https://www.ncbi.nlm.nih.gov/pubmed/27446084
http://dx.doi.org/10.3389/fimmu.2016.00254