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Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies()
Human serum IgG contains multiple glycoforms which exhibit a range of binding properties to effector molecules such as cellular Fc receptors. Emerging knowledge of how the Fc glycans contribute to the antibody structure and effector functions has opened new avenues for the exploitation of defined an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922387/ https://www.ncbi.nlm.nih.gov/pubmed/27105835 http://dx.doi.org/10.1016/j.bbagen.2016.04.016 |