EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen

Chordoma is a rare malignant bone tumour with a poor prognosis and limited therapeutic options. We undertook a focused compound screen (FCS) against 1097 compounds on three well‐characterized chordoma cell lines; 154 compounds were selected from the single concentration screen (1 µm), based on their...

Descripción completa

Detalles Bibliográficos
Autores principales: Scheipl, Susanne, Barnard, Michelle, Cottone, Lucia, Jorgensen, Mette, Drewry, David H, Zuercher, William J, Turlais, Fabrice, Ye, Hongtao, Leite, Ana P, Smith, James A, Leithner, Andreas, Möller, Peter, Brüderlein, Silke, Guppy, Naomi, Amary, Fernanda, Tirabosco, Roberto, Strauss, Sandra J, Pillay, Nischalan, Flanagan, Adrienne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922416/
https://www.ncbi.nlm.nih.gov/pubmed/27102572
http://dx.doi.org/10.1002/path.4729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922416/
https://www.ncbi.nlm.nih.gov/pubmed/27102572
http://dx.doi.org/10.1002/path.4729

Ejemplares similares