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Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways

Mitochondrial morphology is dynamically remodeled by fusion and fission in cells, and dysregulation of this process is closely implicated in tumorigenesis. However, the mechanism by which mitochondrial dynamics influence cancer cell survival is considerably less clear, especially in hepatocellular c...

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Detalles Bibliográficos
Autores principales: Huang, Qichao, Zhan, Lei, Cao, Haiyan, Li, Jibin, Lyu, Yinghua, Guo, Xu, Zhang, Jing, Ji, Lele, Ren, Tingting, An, Jiaze, Liu, Bingrong, Nie, Yongzhan, Xing, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922447/
https://www.ncbi.nlm.nih.gov/pubmed/27124102
http://dx.doi.org/10.1080/15548627.2016.1166318