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Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease

Objectives: To quantify islet cell nucleomegaly in controls and tissues obtained from patients with congenital hyperinsulinism in infancy (CHI) and to examine the association of nucleomegaly with proliferation. Methods: High-content analysis of histologic sections and serial block-face scanning elec...

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Detalles Bibliográficos
Autores principales: Han, Bing, Newbould, Melanie, Batra, Gauri, Cheesman, Edmund, Craigie, Ross J., Mohamed, Zainab, Rigby, Lindsey, Padidela, Raja, Skae, Mars, Mironov, Aleksandr, Starborg, Tobias, Kadler, Karl E., Cosgrove, Karen E., Banerjee, Indraneel, Dunne, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922485/
https://www.ncbi.nlm.nih.gov/pubmed/27334808
http://dx.doi.org/10.1093/ajcp/aqw075