Acetate mediates a microbiome-brain-β cell axis promoting metabolic syndrome

Obesity, insulin resistance and the metabolic syndrome are associated with changes to the gut microbiota; however, the mechanism by which modifications to the gut microbiota might lead to these conditions is unknown. Here we show that increased production of acetate by an altered gut microbiota lead...

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Detalles Bibliográficos
Autores principales: Perry, Rachel J., Peng, Liang, Barry, Natasha A., Cline, Gary W., Zhang, Dongyan, Cardone, Rebecca L., Petersen, Kitt Falk, Kibbey, Richard G., Goodman, Andrew L., Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922538/
https://www.ncbi.nlm.nih.gov/pubmed/27279214
http://dx.doi.org/10.1038/nature18309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922538/
https://www.ncbi.nlm.nih.gov/pubmed/27279214
http://dx.doi.org/10.1038/nature18309

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