Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues

The immature phenotype of stem cell derived cardiomyocytes is a significant barrier to their use in translational medicine and pre-clinical in vitro drug toxicity and pharmacological analysis. Here we have assessed the contribution of non-myocyte cells on the contractile function of co-cultured huma...

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Detalles Bibliográficos
Autores principales: Ravenscroft, Stephanie M., Pointon, Amy, Williams, Awel W., Cross, Michael J., Sidaway, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Function of Non-Myocyte Cells Derived from Stem Cell Cardiomyocyte Model
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922542/
https://www.ncbi.nlm.nih.gov/pubmed/27125969
http://dx.doi.org/10.1093/toxsci/kfw069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922542/
https://www.ncbi.nlm.nih.gov/pubmed/27125969
http://dx.doi.org/10.1093/toxsci/kfw069

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