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Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues

The immature phenotype of stem cell derived cardiomyocytes is a significant barrier to their use in translational medicine and pre-clinical in vitro drug toxicity and pharmacological analysis. Here we have assessed the contribution of non-myocyte cells on the contractile function of co-cultured huma...

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Detalles Bibliográficos
Autores principales:	Ravenscroft, Stephanie M., Pointon, Amy, Williams, Awel W., Cross, Michael J., Sidaway, James E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Function of Non-Myocyte Cells Derived from Stem Cell Cardiomyocyte Model
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922542/ https://www.ncbi.nlm.nih.gov/pubmed/27125969 http://dx.doi.org/10.1093/toxsci/kfw069

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