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Dimethyl Sulfoxide Perturbs Cell Cycle Progression and Spindle Organization in Porcine Meiotic Oocytes

Meiotic maturation of mammalian oocytes is a precisely orchestrated and complex process. Dimethyl sulfoxide (DMSO), a widely used solvent, drug, and cryoprotectant, is capable of disturbing asymmetric cytokinesis of oocyte meiosis in mice. However, in pigs, DMSO’s effect on oocyte meiosis still rema...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Wang, Yan-Kui, Song, Zhi-Qiang, Du, Zhi-Qiang, Yang, Cai-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922549/
https://www.ncbi.nlm.nih.gov/pubmed/27348312
http://dx.doi.org/10.1371/journal.pone.0158074