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Bisphenol A-associated alterations in genome-wide DNA methylation and gene expression patterns reveal sequence-dependent and non-monotonic effects in human fetal liver

Bisphenol A (BPA), a high production volume chemical widely used in consumer products, is an endocrine active compound associated with complex epigenetic responses in animal models and humans. Developmental BPA exposure in mice previously revealed widespread changes in the mouse liver methylome. Her...

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Detalles Bibliográficos
Autores principales: Faulk, Christopher, Kim, Jung H., Jones, Tamara R., McEachin, Richard C., Nahar, Muna S., Dolinoy, Dana C., Sartor, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922640/
https://www.ncbi.nlm.nih.gov/pubmed/27358748
http://dx.doi.org/10.1093/eep/dvv006