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Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche

The crypts of the intestinal epithelium house the stem cells that ensure the continual renewal of the epithelial cells that line the intestinal tract. Crypt number increases by a process called crypt fission, the division of a single crypt into two daughter crypts. Fission drives normal tissue growt...

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Detalles Bibliográficos
Autores principales: Langlands, Alistair J., Almet, Axel A., Appleton, Paul L., Newton, Ian P., Osborne, James M., Näthke, Inke S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922642/
https://www.ncbi.nlm.nih.gov/pubmed/27348469
http://dx.doi.org/10.1371/journal.pbio.1002491