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L-Tryptophan Production in Escherichia coli Improved by Weakening the Pta-AckA Pathway

Acetate accumulation during the fermentation process of Escherichia coli FB-04, an L-tryptophan production strain, is detrimental to L-tryptophan production. In an initial attempt to reduce acetate formation, the phosphate acetyltransferase gene (pta) from E. coli FB-04 was deleted, forming strain F...

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Detalles Bibliográficos
Autores principales: Liu, Lina, Duan, Xuguo, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922666/
https://www.ncbi.nlm.nih.gov/pubmed/27348810
http://dx.doi.org/10.1371/journal.pone.0158200