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L-Tryptophan Production in Escherichia coli Improved by Weakening the Pta-AckA Pathway
Acetate accumulation during the fermentation process of Escherichia coli FB-04, an L-tryptophan production strain, is detrimental to L-tryptophan production. In an initial attempt to reduce acetate formation, the phosphate acetyltransferase gene (pta) from E. coli FB-04 was deleted, forming strain F...
Autores principales: | Liu, Lina, Duan, Xuguo, Wu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922666/ https://www.ncbi.nlm.nih.gov/pubmed/27348810 http://dx.doi.org/10.1371/journal.pone.0158200 |
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