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Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

The ability to detect and/or manipulate specific cell populations based upon the presence of intracellular protein epitopes would enable many types of studies and applications. Protein binders such as nanobodies (Nbs) can target untagged proteins (antigens) in the intracellular environment. However,...

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Detalles Bibliográficos
Autores principales: Tang, Jonathan CY, Drokhlyansky, Eugene, Etemad, Behzad, Rudolph, Stephanie, Guo, Binggege, Wang, Sui, Ellis, Emily G, Li, Jonathan Z, Cepko, Constance L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922844/
https://www.ncbi.nlm.nih.gov/pubmed/27205882
http://dx.doi.org/10.7554/eLife.15312