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Dynamic Regulation of TCR–Microclusters and the Microsynapse for T Cell Activation

The interaction between a T cell and an antigen-presenting cell is the initiating event in T cell-mediated adaptive immunity. The Immunological Synapse (IS) is formed at the interface between these two cell types, and is the site where antigen (Ag)-specific recognition and activation are induced thr...

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Detalles Bibliográficos
Autores principales: Hashimoto-Tane, Akiko, Saito, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923147/
https://www.ncbi.nlm.nih.gov/pubmed/27446085
http://dx.doi.org/10.3389/fimmu.2016.00255