Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP(+) and Rotenone Toxicity

The G-protein coupled receptor 139 (GPR139) is expressed specifically in the brain in areas of relevance for motor control. GPR139 function and signal transduction pathways are elusive, and results in the literature are even contradictory. Here, we examined the potential neuroprotective effect of GP...

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Detalles Bibliográficos
Autores principales: Bayer Andersen, Kirsten, Leander Johansen, Jens, Hentzer, Morten, Smith, Garrick Paul, Dietz, Gunnar P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923153/
https://www.ncbi.nlm.nih.gov/pubmed/27445691
http://dx.doi.org/10.3389/fncel.2016.00164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923153/
https://www.ncbi.nlm.nih.gov/pubmed/27445691
http://dx.doi.org/10.3389/fncel.2016.00164

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