Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high‐calorie diet

Heterozygous mutations of the Hfe gene have been proposed as cofactors in the development and progression of nonalcoholic fatty liver disease (NAFLD). Homozygous Hfe deletion previously has been shown to lead to dysregulated hepatic lipid metabolism and accentuated liver injury in a dietary mouse mo...

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Detalles Bibliográficos
Autores principales: Britton, Laurence, Jaskowski, Lesley, Bridle, Kim, Santrampurwala, Nishreen, Reiling, Janske, Musgrave, Nick, Subramaniam, V. Nathan, Crawford, Darrell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923236/
https://www.ncbi.nlm.nih.gov/pubmed/27354540
http://dx.doi.org/10.14814/phy2.12837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923236/
https://www.ncbi.nlm.nih.gov/pubmed/27354540
http://dx.doi.org/10.14814/phy2.12837

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