Hypoxia and hyperoxia potentiate PAF receptor‐mediated effects in newborn ovine pulmonary arterial smooth muscle cells: significance in oxygen therapy of PPHN

Platelet‐activating factor (PAF) acting via its receptor (PAFR) is implicated in the pathogenesis of persistent pulmonary hypertension of the newborn (PPHN). Effects of long‐term oxygen therapy on newborn lung are not well understood; therefore, we studied the effect of oxygen tension on ovine newbo...

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Detalles Bibliográficos
Autores principales: Hanouni, Mona, Bernal, Gilberto, McBride, Shaemion, Narvaez, Vincent Reginald F., Ibe, Basil O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923239/
https://www.ncbi.nlm.nih.gov/pubmed/27354543
http://dx.doi.org/10.14814/phy2.12840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923239/
https://www.ncbi.nlm.nih.gov/pubmed/27354543
http://dx.doi.org/10.14814/phy2.12840

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