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Hypoxia and hyperoxia potentiate PAF receptor‐mediated effects in newborn ovine pulmonary arterial smooth muscle cells: significance in oxygen therapy of PPHN
Platelet‐activating factor (PAF) acting via its receptor (PAFR) is implicated in the pathogenesis of persistent pulmonary hypertension of the newborn (PPHN). Effects of long‐term oxygen therapy on newborn lung are not well understood; therefore, we studied the effect of oxygen tension on ovine newbo...
Autores principales: | Hanouni, Mona, Bernal, Gilberto, McBride, Shaemion, Narvaez, Vincent Reginald F., Ibe, Basil O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923239/ https://www.ncbi.nlm.nih.gov/pubmed/27354543 http://dx.doi.org/10.14814/phy2.12840 |
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