ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy

Highlights: ASS2324 is a hybrid compound resulting from the juxtaposition of donepezil and the propargylamine PF9601N. ASS2324 is a multi-target directed propargylamine able to bind to all the AChE/BuChE and MAO A/B enzymes. ASS2324 shows antioxidant, neuroprotective and suitable permeability proper...

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Detalles Bibliográficos
Autores principales: Marco-Contelles, José, Unzeta, Mercedes, Bolea, Irene, Esteban, Gerard, Ramsay, Rona R., Romero, Alejandro, Martínez-Murillo, Ricard, Carreiras, M. Carmo, Ismaili, Lhassane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923252/
https://www.ncbi.nlm.nih.gov/pubmed/27445665
http://dx.doi.org/10.3389/fnins.2016.00294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923252/
https://www.ncbi.nlm.nih.gov/pubmed/27445665
http://dx.doi.org/10.3389/fnins.2016.00294

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