A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABA(A)R and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing

GABA(A)Rs and GlyRs are considered attractive drug targets for therapeutic intervention and are also increasingly recognized in the context of in vitro neurotoxicity (NT) and developmental neurotoxicity (DNT) testing. However, systematic human-specific GABA(A)R and GlyR-targeted drug screening and t...

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Detalles Bibliográficos
Autores principales: Kuenzel, Katharina, Friedrich, Oliver, Gilbert, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923258/
https://www.ncbi.nlm.nih.gov/pubmed/27445687
http://dx.doi.org/10.3389/fnmol.2016.00051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923258/
https://www.ncbi.nlm.nih.gov/pubmed/27445687
http://dx.doi.org/10.3389/fnmol.2016.00051

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