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A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABA(A)R and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing
GABA(A)Rs and GlyRs are considered attractive drug targets for therapeutic intervention and are also increasingly recognized in the context of in vitro neurotoxicity (NT) and developmental neurotoxicity (DNT) testing. However, systematic human-specific GABA(A)R and GlyR-targeted drug screening and t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923258/ https://www.ncbi.nlm.nih.gov/pubmed/27445687 http://dx.doi.org/10.3389/fnmol.2016.00051 |