Allospecific Tregs Expanded After Anergization Remain Suppressive in Inflammatory Conditions but Lack Expression of Gut-homing Molecules

Cell therapy with antigen-specific regulatory T-cells (Treg) has great potential to selectively control unwanted immune responses after allogeneic stem-cell or solid organ transplantation and in autoimmune diseases. Ex vivo allostimulation with costimulatory blockade (alloanergization) of human T-ce...

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Detalles Bibliográficos
Autores principales: Kotsiou, Eleni, Gribben, John G, Davies, Jeff K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923329/
https://www.ncbi.nlm.nih.gov/pubmed/27049761
http://dx.doi.org/10.1038/mt.2016.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923329/
https://www.ncbi.nlm.nih.gov/pubmed/27049761
http://dx.doi.org/10.1038/mt.2016.64

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